Company	Share, %
Aadi Bioscience, Inc.	11.6
CymaBay Therapeutics, Inc.	9.69
Mirati Therapeutics, Inc.	9.5
Amicus Therapeutics, Inc.	9.28
Apellis Pharmaceuticals, Inc.	9.21
Madrigal Pharmaceuticals, Inc.	9.12
Krystal Biotech, Inc.	9
Monte Rosa Therapeutics, Inc.	8.98
DICE Therapeutics, Inc.	8.28
Xenon Pharmaceuticals Inc.	7.51
Verrica Pharmaceuticals Inc.	7.02
Ascendis Pharma A/S	6.81
BioCryst Pharmaceuticals, Inc.	6.33
Marinus Pharmaceuticals, Inc.	6.23
Kymera Therapeutics, Inc.	6.18
United Therapeutics Corporation	6.08
Kura Oncology, Inc.	5.05
Structure Therapeutics Inc.	5.01
Syndax Pharmaceuticals, Inc.	4.97
IVERIC bio, Inc.	4.94
Sarepta Therapeutics, Inc.	4.63
Fennec Pharmaceuticals Inc.	4.43
Cerevel Therapeutics Holdings, Inc.	4.16
Horizon Therapeutics Public Limited Company	3.06
Soleno Therapeutics, Inc.	2.42
Iovance Biotherapeutics, Inc.	2.4
Taysha Gene Therapies, Inc.	2.33
Intra-Cellular Therapies, Inc.	2.33
BioMarin Pharmaceutical	2.28
argenx SE	2.08
Tango Therapeutics, Inc.	1.85