NASDAQ: PRTA - Prothena Corporation plc

Yield per half year: -32.47%
Dividend yield: 0.00%
Sector: Healthcare

Share chart Prothena Corporation plc

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About Prothena Corporation plc

Prothena Corporation plc, компания, занимающаяся клиническими исследованиями в области нейробиологии, специализируется на открытии и разработке новых методов лечения опасных для жизни заболеваний в Соединенных Штатах. Компания участвует в разработке PRX002 / RG7935, которая находится в фазе II клинических испытаний для лечения болезни Паркинсона и других родственных синуклеинопатий; и PRX004, антитело, которое проходит фазу I клинических испытаний для лечения амилоидоза ATTR.

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Его программы на стадии открытия включают тау-белок для лечения болезни Альцгеймера, прогрессирующего надъядерного паралича, лобно-височной деменции, хронической травматической энцефалопатии и других таупатий; Aß, или амилоид-бета, белок для лечения болезни Альцгеймера; TDP-43 при боковом амиотрофическом склерозе и лобно-височной деменции; и другие продукты для нейродегенерации. Компания имеет лицензию, соглашение о разработке и коммерциализации с F. Hoffmann-La Roche Ltd и Hoffmann-La Roche Inc. на разработку и коммерциализацию антител, нацеленных на альфа-синуклеин; и соглашение о сотрудничестве с Bristol-Myers Squibb для разработки антител. Prothena Corporation plc была основана в 2012 году и находится в Дублине, Ирландия.
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IPO date 2012-12-21
ISIN IE00B91XRN20
Industry Biotechnology
Sector Health Care
Валюта usd
Валюта отчета usd
Див.доход ао 0
Сайт http://www.prothena.com
Цена ао 13.05
Change price per day: +0.9044% (15.48)
Change price per week: +13.44% (13.77)
Change price per month: +1.43% (15.4)
Change price per 3 month: +2.09% (15.3)
Change price per half year: -32.47% (23.13)
Change price per year: -52.13% (32.63)
Change price per 3 year: -56.59% (35.98)
Change price per 5 year: +26.38% (12.36)
Change price per 10 year: 0% (15.62)
Change price per year to date: -2.44% (16.01)
All parameters

Underestimation

Title Value Grade
P/S 22.87 1
P/BV 3.72 5
P/E 18.28 7
EV/EBITDA -7.79 0
Total: 4.25

Efficiency

Title Value Grade
ROA, % -21.11 0
ROE, % -26.19 0
Total: 1

Dividends

Title Value Grade
Div yield, % 0 0
DSI 0 0
Total: 0

Debt

Title Value Grade
Debt/EBITDA -0.0623 10
Total: 8.8

Growth impulse

Title Value Grade
Yield Revenue, % 11124.82 10
Yield Ebitda, % 121.57 10
Yield EPS, % 41.68 6
Total: 9
More

Transaction date Date of disclosure Insider Type Price Volume Quantity Share before, % Share after, % Document
30.11.2023 30.11.2023 Walker Karin L
Chief Accounting Officer		 Sale 34 170 000 5000 0 -0.01 link
30.11.2023 30.11.2023 Walker Karin L
Chief Accounting Officer		 Purchase 13.53 67 650 5000 0 0.01 link
27.09.2023 27.09.2023 Malecek Michael J
Chief Legal Officer		 Sale 47.38 236 900 5000 0 -0.01 link
27.09.2023 27.09.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
13.09.2023 13.09.2023 Smith Brandon S.
Chief Operating Officer		 Sale 55.49 221 960 4000 0 -0.01 link
13.09.2023 13.09.2023 Smith Brandon S.
Chief Operating Officer		 Purchase 11.12 44 480 4000 0 0.01 link
13.09.2023 13.09.2023 Garren Hideki
Chief Medical Officer		 Sale 55.48 110 960 2000 0 0 link
13.09.2023 13.09.2023 Garren Hideki
Chief Medical Officer		 Purchase 24.9 49 800 2000 0 0 link
30.08.2023 30.08.2023 Malecek Michael J
Chief Legal Officer		 Sale 55.01 275 050 5000 0 -0.01 link
30.08.2023 30.08.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
18.08.2023 18.08.2023 Walker Karin L
Chief Accounting Officer		 Sale 57.18 285 900 5000 0 -0.01 link
18.08.2023 18.08.2023 Walker Karin L
Chief Accounting Officer		 Purchase 15.04 75 200 5000 0 0.01 link
26.07.2023 26.07.2023 Malecek Michael J
Chief Legal Officer		 Sale 62.33 311 650 5000 0 -0.01 link
26.07.2023 26.07.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
12.07.2023 12.07.2023 Smith Brandon S.
Chief Operating Officer		 Sale 67.51 270 040 4000 0 -0.01 link
12.07.2023 12.07.2023 Smith Brandon S.
Chief Operating Officer		 Purchase 11.12 44 480 4000 0 0.01 link
12.07.2023 12.07.2023 Garren Hideki
Chief Medical Officer		 Sale 67.51 135 020 2000 0 0 link
12.07.2023 12.07.2023 Garren Hideki
Chief Medical Officer		 Purchase 24.9 49 800 2000 0 0 link
03.07.2023 03.07.2023 Selkoe Dennis J.
Director		 Sale 67.43 337 150 5000 0 -0.01 link
03.07.2023 03.07.2023 Selkoe Dennis J.
Director		 Purchase 11.33 56 650 5000 0 0.01 link
28.06.2023 28.06.2023 Malecek Michael J
Chief Legal Officer		 Sale 69.82 349 100 5000 0 -0.01 link
28.06.2023 28.06.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
16.06.2023 16.06.2023 Garren Hideki
Chief Medical Officer		 Sale 74 542 494 7331 0 -0.02 link
16.06.2023 16.06.2023 Garren Hideki
Chief Medical Officer		 Purchase 24.9 182 542 7331 0 0.02 link
19.05.2023 19.05.2023 Walker Karin L
Chief Accounting Officer		 Sale 74 370 000 5000 0 -0.01 link
19.05.2023 19.05.2023 Walker Karin L
Chief Accounting Officer		 Purchase 15.04 75 200 5000 0 0.01 link
03.05.2023 05.05.2023 Selkoe Dennis J.
Director		 Sale 57 855 000 15000 0 -0.03 link
03.05.2023 05.05.2023 Selkoe Dennis J.
Director		 Purchase 18.07 271 050 15000 0 0.03 link
26.04.2023 28.04.2023 Malecek Michael J
Chief Legal Officer		 Sale 53.46 267 300 5000 0 -0.01 link
26.04.2023 28.04.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
19.04.2023 21.04.2023 Walker Karin L
Chief Accounting Officer		 Sale 52.9 264 500 5000 0 -0.01 link
19.04.2023 21.04.2023 Walker Karin L
Chief Accounting Officer		 Purchase 15.04 75 200 5000 0 0.01 link
29.03.2023 31.03.2023 Malecek Michael J
Chief Legal Officer		 Sale 49.02 245 100 5000 0 -0.01 link
29.03.2023 31.03.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 51 350 5000 0 0.01 link
15.03.2023 17.03.2023 Garren Hideki
Chief Medical Officer		 Sale 48.41 580 920 12000 0 -0.03 link
15.03.2023 17.03.2023 Garren Hideki
Chief Medical Officer		 Purchase 24.9 298 800 12000 0 0.03 link
15.03.2023 17.03.2023 Malecek Michael J
Chief Legal Officer		 Sale 48.44 726 600 15000 0 -0.03 link
15.03.2023 17.03.2023 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 154 050 15000 0 0.03 link
15.03.2023 17.03.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 48.43 484 300 10000 0 -0.02 link
15.03.2023 17.03.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
15.03.2023 17.03.2023 Walker Karin L
Chief Accounting Officer		 Sale 48.42 968 400 20000 0 -0.04 link
15.03.2023 17.03.2023 Walker Karin L
Chief Accounting Officer		 Purchase 15.04 300 800 20000 0 0.04 link
15.02.2023 17.02.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 53.34 533 400 10000 0 -0.02 link
15.02.2023 17.02.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
18.01.2023 20.01.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 55.53 555 300 10000 0 -0.02 link
18.01.2023 20.01.2023 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
21.12.2022 23.12.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 58.97 589 700 10000 0 -0.02 link
21.12.2022 23.12.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
23.11.2022 25.11.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 61.09 610 900 10000 0 -0.02 link
23.11.2022 25.11.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
18.11.2022 18.11.2022 Walker Karin L
Chief Accounting Officer		 Sale 57.07 570 700 10000 0 -0.02 link
18.11.2022 18.11.2022 Walker Karin L
Chief Accounting Officer		 Purchase 15.04 150 400 10000 0 0.02 link
10.11.2022 10.11.2022 Cooke Shane
Director		 Sale 56.17 280 850 5000 0 -0.01 link
10.11.2022 10.11.2022 Cooke Shane
Director		 Purchase 6.41 32 050 5000 0 0.01 link
27.10.2022 28.10.2022 Malecek Michael J
Chief Legal Officer		 Sale 62 1 240 000 20000 0 -0.04 link
27.10.2022 28.10.2022 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 205 400 20000 0 0.04 link
26.10.2022 28.10.2022 Malecek Michael J
Chief Legal Officer		 Sale 60.31 3 920 150 65000 0 -0.14 link
26.10.2022 28.10.2022 Malecek Michael J
Chief Legal Officer		 Purchase 10.27 667 550 65000 0 0.14 link
19.10.2022 21.10.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 56.44 564 400 10000 0 -0.02 link
19.10.2022 21.10.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
05.10.2022 07.10.2022 COLLIER RICHARD T
Director		 Sale 57.92 289 600 5000 0 -0.01 link
05.10.2022 07.10.2022 COLLIER RICHARD T
Director		 Purchase 6.41 32 050 5000 0 0.01 link
28.09.2022 30.09.2022 Ekman Lars
Chair of the Board		 Sale 48.09 1 522 820 31666 0 -0.07 link
28.09.2022 30.09.2022 Ekman Lars
Chair of the Board		 Purchase 6.41 202 979 31666 0 0.07 link
28.09.2022 30.09.2022 COLLIER RICHARD T
Director		 Sale 48.09 1 202 250 25000 0 -0.05 link
28.09.2022 30.09.2022 COLLIER RICHARD T
Director		 Purchase 6.41 160 250 25000 0 0.05 link
28.09.2022 30.09.2022 Cooke Shane
Director		 Sale 48.09 480 900 10000 0 -0.02 link
28.09.2022 30.09.2022 Cooke Shane
Director		 Purchase 6.41 64 100 10000 0 0.02 link
28.09.2022 30.09.2022 Kinney Gene G.
President and CEO		 Sale 53.38 876 073 16412 0 -0.04 link
28.09.2022 30.09.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 105 201 16412 0 0.04 link
21.09.2022 23.09.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 30.75 307 500 10000 0 -0.02 link
21.09.2022 23.09.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
21.09.2022 23.09.2022 Kinney Gene G.
President and CEO		 Sale 32.02 87 094 2720 0 -0.01 link
21.09.2022 23.09.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 17 435 2720 0 0.01 link
15.09.2022 16.09.2022 Garren Hideki
Chief Medical Officer		 Sale 30 120 000 4000 0 -0.01 link
15.09.2022 16.09.2022 Garren Hideki
Chief Medical Officer		 Purchase 24.9 99 600 4000 0 0.01 link
24.08.2022 26.08.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 30.17 301 700 10000 0 -0.02 link
24.08.2022 26.08.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 67 300 10000 0 0.02 link
17.08.2022 19.08.2022 Kinney Gene G.
President and CEO		 Sale 32.03 69 857 2181 0 0 link
17.08.2022 19.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 13 980 2181 0 0 link
12.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Sale 32.16 652 333 20284 0 -0.04 link
12.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 130 020 20284 0 0.04 link
11.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Sale 32.16 438 984 13650 0 -0.03 link
11.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 87 497 13650 0 0.03 link
10.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Sale 32.01 31 722 991 0 0 link
10.08.2022 12.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 6 352 991 0 0 link
05.08.2022 05.08.2022 Kinney Gene G.
President and CEO		 Sale 32.83 706 042 21506 0 -0.05 link
05.08.2022 05.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 137 853 21506 0 0.05 link
04.08.2022 05.08.2022 Kinney Gene G.
President and CEO		 Sale 32.18 674 300 20954 0 -0.04 link
04.08.2022 05.08.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 134 315 20954 0 0.04 link
27.07.2022 29.07.2022 Kinney Gene G.
President and CEO		 Sale 32 12 032 376 0 0 link
27.07.2022 29.07.2022 Kinney Gene G.
President and CEO		 Purchase 6.41 2 410 376 0 0 link
22.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 32.55 238 266 7320 0 -0.02 link
22.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 49 264 7320 0 0.02 link
21.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 32.64 671 078 20560 0 -0.04 link
21.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 138 369 20560 0 0.04 link
20.07.2022 22.07.2022 Cooke Shane
Director		 Sale 32.9 493 500 15000 0 -0.03 link
20.07.2022 22.07.2022 Cooke Shane
Director		 Purchase 6.41 96 150 15000 0 0.03 link
20.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Sale 32.49 1 368 480 42120 0 -0.09 link
20.07.2022 22.07.2022 Nguyen Tran
Chief Strategy Officer and CFO		 Purchase 6.73 283 468 42120 0 0.09 link
06.07.2022 08.07.2022 Garren Hideki
Chief Medical Officer		 Sale 30 240 000 8000 0 -0.02 link
06.07.2022 08.07.2022 Garren Hideki
Chief Medical Officer		 Purchase 24.9 199 200 8000 0 0.02 link

Institutions Volume Share, %
EcoR1 Capital, LLC 11584280 21.56
FMR, LLC 8049796 14.98
Price (T.Rowe) Associates Inc 4237351 7.89
Blackrock Inc. 3770650 7.02
State Street Corporation 2758564 5.14
Wellington Management Group, LLP 2594102 4.83
Janus Henderson Group PLC 2035984 3.79
Palo Alto Investors Lp 1660057 3.09
First Light Asset Management, LLC 1088801 2.03
Vanguard Group Inc 1070555 1.99

ETF Share, % Profitability for 1 year, % Dividends, %
iShares Neuroscience and Healthcare ETF 1.87182 19.72 0.03
Virtus LifeSci Biotech Clinical Trials ETF 0.80125 63.04 0.33
Direxion Daily S&P Biotech Bull 3x Shares 0.17559 4067.92 0.25924
Invesco Nasdaq Biotechnology ETF 0.11237 28.58 0.8565
Future Tech ETF 0.11196 426.34 0.8416
Principal Healthcare Innovators ETF 0.11196 618.5 0.8416
ProShares Ultra Nasdaq Biotechnology 0.07689 51.7 0.85651
Nuveen ESG Small-Cap ETF 0.07594 13.91 1.41019
iShares ESG Aware MSCI USA Small-Cap ETF 0.05367 18.09 1.49366
JPMorgan BetaBuilders U.S. Small Cap Equity Fund 0.05031 24.75 1.59225
Vanguard Russell 2000 ETF 0.04 17.16 1.48801
Vanguard Russell 2000 Growth ETF 0.04 23.05 0.60264
iShares Russell 2000 Growth ETF 0.03933 38.04 0.6026
Avantis U.S Small Cap Equity ETF 0.0243 27.77 1.68271
Schwab U.S. Small-Cap ETF 0.02307 17.47 1.51433
ProShares UltraPro Russell2000 0.01985 89.82 1.47873
Goldman Sachs ActiveBeta US Small Cap Equity ETF 0.01808 31.36 1.41955
Invesco FTSE RAFI US 1500 Small-Mid ETF 0.01673 17.58 1.75869
Fidelity MSCI Health Care Index ETF 0.01148 3 1.46057
SPDR Portfolio MSCI Global Stock Market ETF 0.00797 17.99 2.19607
ProShares Hedge Replication ETF 0.00554 5.92 1.47892
Dimensional U.S. Core Equity 2 ETF 0.00285 30.76 1.47098
Schwab U.S. Broad Market ETF 0.00162 24.86 1.43354
iShares Russell 3000 ETF 0.00157 24.83 1.43482
Dimensional US Core Equity Market ETF 0.00113 30.98 1.40618
Dimensional U.S. Equity ETF 0.00054 31.53 1.3557
Vanguard ESG U.S. Stock ETF 0 23.54 1.26927
Vanguard Russell 3000 ETF 0 31.87 1.43817



Head Job title Payment Year of birth
Mr. Tran B. Nguyen M.B.A. CFO & Chief Strategy Officer 762.86k 1974 (51 year)
Mr. Michael J. Malecek Chief Legal Officer 588.25k 1966 (59 years)
Ms. Carol D. Karp Chief Regulatory Officer 697.51k 1953 (72 years)
Mr. Brandon S. Smith Chief Operating Officer 756.41k 1975 (50 years)
Dr. Wagner M. Zago Chief Scientific Officer 478.79k 1973 (52 years)
Dr. Gene G. Kinney Ph.D. President, CEO & Director 1.03M 1969 (56 years)
Dr. Hideki Garren M.D., Ph.D. Chief Medical Officer 809.59k 1965 (60 years)
Mr. Mark C. Johnson C.F.A. Vice President of Investor Relations N/A
Ms. Karin L. Walker CPA Chief Accounting Officer & Controller 1963 (62 years)
Mr. David A. Ford Chief People Officer 1969 (56 years)

Address: Ireland, Dublin , 77 Sir John Rogerson’s Quay - open in Google maps, open in Yandex maps
Website: http://www.prothena.com